Perl, ER, (2007) Ideas about pain, a historical view. Nature Rev Neurosci 8:71-80

Basbaum AL et al (2009)  Cellular and Molecular Mechanisms of Pain. Cell 139: 267-284


Lewin GR et al (2004) A plethora of painful molecules Curr Opin Neurobiol 14: 443-449 
Bandell M et al (2007) From chills to chilis: mechanisms for thermosensation and chemesthesis via thermoTRPs  Curr Opin Neurobiol 17:490-497


Dib-Hajj SD et al (2007) From genes to pain: Nav1.7 and human pain disorder Trends Neurosci 30:555-563  


Weissman, G (1991) Aspirin Sci. Am. 264(1) 58-64  
Vane JR. (2000) The fight against rheumatism: from willow bark to COX-1 sparing drugs. J Physiol Pharmacol. 51:573-86
Warner , TD & Mitchell, JA (2002) Cyclooxygenase-3 (COX-3): Filling in the gaps toward a COX continuum? PNAS 2002 99: 13371-13373.
Ritter M et al (2009) Precaution, cyclooxygenase inhibition, and cardiovascular risk. Trends Pharm Sci 30:503-8

Gate Control hypothesis

Hunt, SP (2000) Pain Control; breaking the circuit. Trends Pharm Sci.21:284-286
Craig, A D B (2003) Pain mechanisms: labeled lines versus convergence in central processing. Ann Rev Neurosci 26:1-30
Sluka, KA & Walsh D (2003) Transcutaneous electrical nerve stimulation... J Pain. 4:109-121
Dickenson AH et al (2004) Bad news from the brain... Trends Pharm Sci 25:613-617
Braz JM et al (2005) Parallel “Pain” Pathways Arise from Subpopulations of Primary Afferent Nociceptor Neuron 47:787-793 

Fields, HL (2011) The Doctor's Dilemma: Opiate Analgesics and Chronic Pain Neuron 69: 591-594
Pasternak, GW (2010) Molecular Insights Into μ Opioid Pharmacology: From the Clinic to the Bench Clin J Pain. 26(Suppl 10): S3–S9. [see also doi:10.1016/j.aat.2010.12.008 ]


Kupers, R & Kehlet H (2006) Brain imaging of clinical pain states: a critical review and
strategies for future studies The Lancet Neurology  5:1033-1044 

Apkaria, AV et al (2004) Human brain mechanisms of pain perception and regulation in health and disease. Eur J Pain 9:463-484 

Borsook D & Becarra L (2009) Emotional Pain without Sensory Pain—Dream On? Neuron 61:153-155


Aspirin and Cyclo-oxygenase - you need the MDL Chime plugin for this - it only works on Windows PCs - see here for  the download  and here on how to install for Firefox

Page last edited by on Nov 23, 2011