Cellular & Molecular Neuroscience - 9

Aim: to know cellular basis of CNS diseases

Suggested reading:



Specific References

Nussbaum and Ellis, (2003) Alzheimer's Disease and Parkinson's Disease N Engl J Med 348:1356-1364

Parkinsons disease:

Youdim MBH, Riederer P (1997) Understanding Parkinson's disease. Scientific American, 276, No.1, pp.52-59 (January issue)

Borlongan, CV Sanberg PR (2002) Neural transplantation for treatment of Parkinson's disease  Drug Discovery Today 7:674-682

Benabid, AL (2003)  Deep brain stimulation for Parkinson's disease  Current Opinion in Neurobiology 13:696-706

Le W & Appel SH (2004) Mutant genes responsible for Parkinson’s disease Curent Opinion in Pharmacology 4: 79-84

Maguire-Zeaiss, KA et al (2004)  Synuclein, dopamine and oxidative stress: co-conspirators in Parkinson's disease? Molecular Brain Res 134:18-23 

Bonini & Giasson (2005)  Snaring the Function of α-Synuclein Cell 123:359-361

Savitt JM et al (2006)  Diagnosis and treatment of Parkinson disease: molecules to medicine J. Clin. Invest. 116:1744-1754  

Wood-Kaczmar, A et al (2006) Understanding the molecular causes of Parkinson's disease   Trends  Mol Med12:521-528


Ross, CA et al (2006) Neurobiology of Schizophrenia Neuron 52:139-153

Snyder SH (2006) Dopamine Receptor Excess and Mouse Madness Neuron 49: 484-485

Alzheimer's disease

Citron M (2004) b-Secretase inhibition for the treatment of Alzheimer's disease – promise and challenge Trends Pharm Sci 25:92-97

Verdile G et al (2004) The role of beta amyloid in Alzheimer’s disease: still a cause of everything or the only one who got caught?   Pharmacological Research 50:397-409  

Goedert, M & Spillantini, MG (2006) A Century of Alzheimer's Disease Science 314:777 - 781  

Roberson, ED & Mucke, L (2006) 100 Years and Counting: Prospects for Defeating Alzheimer's Disease Science, 314:781 - 784

Hardy, J (2006) A Hundred Years of Alzheimer's Disease Research Neuron 52:3-13


The powerpoint presentation (for york.ac.uk computers) is here

page last updated by Chris Elliott, December 8, 2006