Module 404 - Nerve muscle & movement
Jan 2011, the 404 exam will have approximately 8 short answer Questions
to a total of 70 marks, and the other 30 marks will accrue from the
practical writeup. Last year's exam is on the Biology web site - also with answers .
Practical writeup: Students are asked to write up 1 of the 4 session. This will account for 30 marks. Please note the following instructions:
report must be word-processed and all graphs etc. drawn using graphical
packages.Make sure that
you address the questions posed in the schedule: but do so in flowing
text [and not in bulleted text or Q and A format].
- The report should not exceed 1000 words [This to include figure legends but not the Reference List].
- It must be structured as a research paper
with Introduction, Methods, Results, Discussion and Reference List.
should give a background to the experiments and detail their aims, you
may like to refer to a few key papers.
- Methods should be short Normally one line referring to the online handout is enough - but do report aspects of the protocols that
were not in the schedule or that were changed. This will be important
in the jumping practical, where you were asked to devise the human jump
- the results must be described in words and the main
findings highlighted as well as being presented in suitable graphical
or tabular form. The data must be presented in a way that makes your
results clear to the reader. Statistical tests are likely to be
inappropriate (due to the small samples).
- Discussion - the findings should be discussed and placed in the context
of the research literature.
- Reference list - full reference must be
made to information derived from other studies and this must be cited
in the proper format in the text.
- Figures Check that each figure has a proper legend.
Your submission must carry your examination number and not your name. The Deadline is on Monday 13 December.
Ralph J. Greenspan (2007) An Introduction to Nervous Systems (Paperback)
Lectures links to the 2009 versions - these will be updated during term
Cold Spring Harbor Laboratory Press, USA ISBN-13: 978-0879698218
Cellular neuroscience: the way in which the individual nerves of a nervous system work:
nerve conduction, synaptic transmission and sensory transduction, how synapses are
constructed, including how genes control the assembly and plasticity of the nervous system.
These aspects lead to the third year module Cellular and Molecular neuroscience.
Lecture 1 GE Action potential
Lecture 2 GE Synapses
Lecture 3 GE Cellular neuroscience of synapses
Lecture 8 CJHE Actions of insecticides on the nervous system; selectivity for insects
over mammals; resistance mechanisms
Muscle: how muscle fibres generate force and movement. The concept of myosin being a
prototype molecular motor.
Lecture 4 JCS Muscle types, structure, activation and energy use
Lecture 5 JCS Mechanism of Muscle contraction
Lecture 6 JCS Control of Muscle Contraction
Lecture 7 JCS Unconventional myosins and cell biology
Neural control of Movement and behaviour: How animals move. The role of reflexes in
the musculo-skeletal system. Central control and modulation of rhythmic patterns. The role
of sense organs in the selection of behaviour. Evolution of behaviour.
Lecture 9 CJHE Movement on land - Clione video (at UC Caliornia)
Lecture 10 CJHE Jumping, flying, swimming.
Lecture 11 CJHE Evolution of behaviour; from ethology to neuroethology.
Lecture 12 STS Sensory control of behaviour.
Growth and plasticity in the nervous system
Lecture 13 STS Axon guidance and synaptic development
Lecture 14 STS Simple correlates of learning and memory
Lecture 15 CJHE Integration – from action potential and synapse via neuromodulation
and sensory input to evolution. - also fly jump movie
lectures will be supported by 4 practicals, each lasting 3 hour. An
overview of the practicals is available, along with time to attend. The
1. Simulation of action potential
2. Sensory control of Drosophila behaviour
3. Locust jumping - 2010 Results and initial analysis
4. Locust breathing
These will be run on a circus system. Assessment is by a write up: you which choose one! An online copy of the handout is available here.
page last updated by Chris Elliott on 15 Nov 10